
Two things I'm excited about, and really hope are implemented, is a new multi site Admin, and a configurable Dashboard. This is kind of interesting, because at WordCamp Utah 2010, Matt Mullenweg asked Adam Dunford, "if you had a magic wand, what would you change in WordPress?" His response was a cleaner, configurable dashboard. Spot on Adam.
Looks like the WP team is shooting for a mid December release, with a feature freeze in mid October. That's not too far off.
If you haven't already upgraded to WordPress 3, you should do it soon. This is a fantastic release, seems to be very stable, and the further you fall behind the more problems you will encounter.